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Canadian suppliers and buyers offer varied options when it comes to empty gelatinous, pill-like capsules intended to carry medications or powders, called empty capsules. These offerings include differences in color and size, the materials used to make the capsule shells, and other more specific features of the capsules.
Gelatin-based capsules
These are the most common types of empty capsules and are made from the hydrolyzed collagen of animal bones and skin. Gelatin capsules are typically available in sizes ranging from 000 to 4 for filling. Size 00 is the most popular gelatin capsule size used for medicines and dietary supplements, and this is because it is neither too big nor too small. Clear or slightly opaque is the natural color of gelatin capsules, but they can be colored and are mostly red, blue, green, or yellow. These capsules also dissolve fast in the human stomach and are, therefore, mostly recommended for supplements that need to be absorbed quickly.
Vegetable capsules
Vegetable capsules are an alternative to gelatin capsules and are especially suited for vegetarians and vegans. Methylcellulose or hypromellose, which is derived from plant cellulose, is used to make these capsules. Like gelatin capsules, vegetable capsules are available in varying sizes and can also be made opaque or clear. Vegetable capsules take a little longer to dissolve, but in that time, they can carry more acid-sensitive supplements.
Sugar-coated capsules
Sugar-coated capsules, also called enteric-coated capsules, are coated with a layer of sugar to make them easier to swallow, having a sweet taste. The sugar coating is a thin layer of sucrose and other soluble sugars that make the capsule sweeter and reduce the bitter or unpleasant taste of the contents. Sugar-coated capsules are mainly used in pediatric formulations or drugs with an unpleasant taste that require masking. Sugar-coated capsules are not as common or readily available in size and color as hard gelatin or vegetarian capsules.
Pullulan capsules
Pullulan is a polysaccharide secreted by a yeast fungus that is most commonly used to produce these capsules. Pullulan capsules are as clear and shiny as gelatin capsules but are a better option than vegetarian capsules for those who want a more natural option as they are derived from a renewable plant source. They are also suitable for vegans as they are gluten-free and yeast-free. Pullulan capsules are usually available in sizes 00 and 0 and dissolve easily in water for quick absorption of the contents.
Softgel capsules
Softgel capsules are used to enclose liquids, oils, or thick pastes. A gelatin matrix is the most common material used to make softgel capsules, which are molded into the liquid-filled capsule shape. They are especially suited for vitamin E, fish oil, and other oil-based supplements. Softgel capsules are more complex to manufacture than hard capsules and are commonly available in fewer sizes, typically larger than hard capsules. Fish gelatin can also be used to make softgel capsules for the people who avoid regular gelatin made from pork or beef.
The design of empty capsules is the most important factor that Canadian suppliers and buyers consider. It affects the functionality, aesthetic appeal, and marketability of the products. The design consists of various aspects such as the shape, color, size, and type of coating of the capsule. Each of these factors plays an important role in determining the capsule's suitability for carrying a range of medication, supplements, and other nutritional products.
Shape
Cylindrical capsule shells that fit into one another to form a sealed container for the capsule contents are the most commonly used shape of capsule in Canada. There are also other shapes of capsules such as oblong, oval, and square capsules, but they are rarely used. Uniquely shaped capsules also provide an opportunity for brand differentiation and may be developed on a custom basis for specific products.
Sizes
Capsules, whether hard or soft, are available in various sizes in the Canadian market. The most popular sizes range from 000, the largest size, to 4, the smallest. Size 00 is most frequently used for pharmaceutical and nutraceutical applications. Larger sizes are suited for carrying greater volumes of powder or other substances, while smaller sizes are used for more concentrated fillings.
Color and printing
Plastic dye is used to color capsules in different brilliant colors, making them more appealing. Blue, red, yellow, and green are the more common colors of capsules. Printing capabilities on capsules with logos, dosage instructions, or other branding elements are available to most Canadian suppliers. This aids companies in distinguishing their products and carrying out more effective marketing.
Coatings
Enteric coatings, which dissolve in the intestines and not the stomach, are used to cover some capsules in Canada. This is especially useful for medications or supplements that are sensitive to stomach acid. Other types of coatings are used for extended or controlled release of drug formulations, such as polymer or lipid-based coatings.
Customization
Many capsule manufacturers in Canada offer customized solutions to meet specific client requirements. This includes the creation of capsules in unique shapes, sizes, colors, and coating types. Capsules can also be customized to meet the needs of specific target markets or to help a brand stand out in a competitive industry.
Many Canadians and businesses use empty capsules in many situations to deliver medications, nutritional supplements, and herbal remedies. Common applications for these capsules revolve around the pharmaceutical, nutraceutical, and herbal sectors, which have distinct requirements for encapsulation. The versatility of empty capsules also creates opportunities for customization, enhancing targeted drug delivery and potentially improving patient compliance and health outcomes.
Pharmaceutical applications
Still widely used in the pharmaceutical industry to deliver medications in a controlled manner, empty capsules allow for precise dosing. This is particularly relevant in medications where the amount to be taken varies from patient to patient and requires very close measurement, such as in highly potent or sensitive drugs. The flexibility of encapsulation enables the combination of multiple drugs within a single capsule for double zero capsules or timed-release formulations, especially in the pharmaceuticals.
Nutraceutical applications
Nutraceuticals, a portmanteau of "nutrition" and "pharmaceutical," refers to foods or food supplements that are claimed to have medicinal or health-giving properties. Empty capsules are commonly used in the Canadian market to contain vitamins, minerals, and dietary supplements. These capsules are typically preferred by buyers and suppliers when dealing with powders, herbal extracts, and other concentrated substances. This is because they mask unpleasant tastes and allow for precise dosages. The demand for custom-sized and colored capsules to suit particular branding strategies further drives the market in this sector.
Herbal remedies
As the gelatin capsules are preferred for containing powdered herbs, they are the most widely used form of encapsulation in the herbal industry. Users of herbal supplements prefer encapsulated forms over tablets and other forms of drugs because of the better absorption rates. It also enables the delivery of hard-to-swallow herbs in powder form in a capsule that can be easily swallowed. Many herbalists also offer empty capsule filling machines that enable their customers to fill the capsules themselves with custom herbal blends.
Custom encapsulation
Many Canadian suppliers provide custom encapsulation services, allowing customers to specify the type, size, color, and coating of the capsule. This is particularly useful for businesses looking to differentiate their products in a crowded market or those needing specific capsule designs for unique formulations. Custom encapsulation can also cater to niche markets, such as organic, gluten-free, or allergy-friendly products, attracting customers with specific dietary needs.
To ensure quality, safety, and performance, understanding the specifications and maintenance related to empty capsules is vital to buyers considering them for diverse applications. Knowledge of capsule specifications is also vital for quality control and customer satisfaction in industries that require these capsules, such as pharmaceuticals and nutraceuticals.
Quality standards
Empty capsule quality should conform to certain standards to ensure it is safe for use and does contain quality and purity products. The Canadian Health and Safety Authority, which helps and collaborates with the capsule filling machine users, gives guidance on the specifications and quality criteria these empty capsules should meet to be considered safe to use. This includes stipulations about capsule size, moisture content, and absence of contaminants such as heavy metals or microbes. Many capsule manufacturers in Canada adhere to good manufacturing practices (GMP) and the ISO certification standard to mitigate this risk further.
Storage conditions
To maintain the integrity of empty capsules, it is essential to store them under appropriate conditions. Capsules should be kept in a cool, dry place, away from direct sunlight and extreme temperatures, which can cause capsules to become brittle, lose their shape, or, in the case of gelatin capsules, become sticky. The humidity level should also be controlled since excess moisture can cause capsules to deform, stick together, or even develop mold in the case of vegetable-based capsules.
Hygiene practices
Hygenic practices are very important when handling empty capsules, especially in healthcare and pharmaceutical settings. It is very important to wash hands before handling capsules to avoid contaminating the capsule with dirt or bacteria. Users who handle capsules in bulk, such as in manufacturing or commercial settings, may consider using gloves or sanitizing their hands between handling. Sanitizing the work area is also recommended to avoid contamination of capsules in the capsules or on the work surfaces.
Testing for quality assurance
Certain quality tests can be carried out on empty capsules to establish whether they are of good quality and fit for use. These tests include checking for moisture content, purity, and capsule size and weight consistency. Dissolution tests can also be done to ensure that capsules will dissolve properly once ingested. Many companies use these tests as part of their quality control process to ensure the integrity and safety of the end products they manufacture using these empty capsules.
Some frequently asked questions about empty capsules Canada offer insights into common concerns or interests regarding aspects like capsule types, customizations, and bulk purchasing options. Addressing these questions can also help businesses make informed decisions about their capsule needs, impacting cost-effectiveness, branding, and product quality.
Can I customize the size and color of empty capsules?
Many capsule suppliers in Canada offer customization options for size, color, and type of coating to meet clients' unique needs. Custom capsules enable companies to stand out in a crowded market by creating distinctive products that cater to specific consumer requirements or branding strategies.
Are vegetarian capsules a suitable alternative to gelatin capsules?
Vegetable capsules made from plant-derived materials like cellulose are an ideal alternative to gelatin capsules. They are particular to a vegan or vegetarian clientele and consumers avoiding animal-derived products for religious or health reasons. While often slightly more expensive, vegetable capsules are versatile and widely used in the vitamins and dietary supplements market.
What are the most common sizes of empty capsules available in Canada?
The most common sizes of empty capsules Canada offers are from size 000 to size 4, with size 00 being the most widely available. Larger sizes are suitable for containing larger quantities of powder or other fill materials, while smaller sizes are used when the fill is in greater quantity to achieve efficient encapsulation.
Are sugar-coated capsules available in Canada?
Yes, sugar-coated capsules are available, although they are less common than hard-shelled gelatin or vegetarian capsules. Sugar-coated capsules are frequently used in pediatric medicines because their sweet coating makes them easier to swallow and suitable for drugs and supplements requiring taste masking.
Can I purchase empty capsules in bulk?
Many capsule suppliers in Canada cater to businesses by providing empty capsules in large quantities. Buying in volume commonly results in significant cost savings, especially for companies producing large amounts of supplements, medications, or custom formulations.